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| 1 | Pirates of the Caribbean: Dead Man's Chest | $62,345,264 | 4,133 | $15,085 | $258,364,766 | -54.0 | 2 | Buena Vista |
| 2 | Little Man | $21,613,176 | 2,533 | $8,533 | $21,613,176 | -- | 1 | Sony |
| 3 | You, Me, and Dupree | $21,525,560 | 3,131 | $6,875 | $21,525,560 | -- | 1 | Universal |
| 4 | Superman Returns | $12,288,317 | 3,765 | $3,264 | $164,316,103 | -43.7 | 3 | Warner Bros. |
| 5 | The Devil Wears Prada | $10,386,386 | 2,810 | $3,696 | $83,490,860 | -30.8 | 3 | Fox |
| 6 | Cars | $7,840,985 | 3,003 | $2,611 | $220,001,446 | -27.0 | 6 | Buena Vista |
| 7 | Click | $7,261,361 | 3,296 | $2,203 | $119,963,211 | -39.1 | 4 | Sony |
| 8 | The Lake House | $1,665,485 | 1,710 | $974 | $48,996,220 | -41.7 | 5 | Warner Bros. |
| 9 | Nacho Libre | $1,615,331 | 1,501 | $1,076 | $77,233,137 | -51.6 | 5 | Paramount |
| 10 | A Scanner Darkly | $1,266,427 | 216 | $5,863 | $1,868,905 | 223.3 | 1 | Warner Ind. |