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| 1 | Click | $40,011,365 | 3,749 | $10,673 | $40,011,365 | -- | 1 | Sony |
| 2 | Cars | $23,285,367 | 3,949 | $5,897 | $156,664,916 | -31.0 | 3 | Buena Vista |
| 3 | Nacho Libre | $12,699,864 | 3,083 | $4,119 | $53,221,306 | -55.1 | 2 | Paramount |
| 4 | The Fast and the Furious: Tokyo Drift | $9,801,835 | 3,030 | $3,235 | $43,144,240 | -59.1 | 2 | Universal |
| 5 | Waist Deep | $9,404,180 | 1,004 | $9,367 | $9,404,180 | -- | 1 | Focus |
| 6 | The Lake House | $8,832,259 | 2,645 | $3,339 | $29,774,472 | -35.1 | 2 | Warner Bros. |
| 7 | The Break-Up | $6,596,625 | 2,906 | $2,270 | $104,235,420 | -32.9 | 4 | Universal |
| 8 | Garfield: A Tail of Two Kitties | $5,209,818 | 2,981 | $1,748 | $16,483,101 | -28.5 | 2 | Fox |
| 9 | X-Men: The Last Stand | $4,841,950 | 2,408 | $2,011 | $224,506,162 | -38.1 | 5 | Fox |
| 10 | The Da Vinci Code | $4,050,844 | 1,911 | $2,120 | $205,589,742 | -23.1 | 6 | Sony |