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| 1 | Cars | $33,731,634 | 3,988 | $8,458 | $117,055,283 | -43.9 | 2 | Buena Vista |
| 2 | Nacho Libre | $28,309,599 | 3,070 | $9,221 | $28,309,599 | -- | 1 | Paramount |
| 3 | The Fast and the Furious: Tokyo Drift | $23,973,840 | 3,027 | $7,920 | $23,973,840 | -- | 1 | Universal |
| 4 | The Lake House | $13,616,196 | 2,645 | $5,148 | $13,616,196 | -- | 1 | Warner Bros. |
| 5 | The Break-Up | $9,831,145 | 3,146 | $3,125 | $92,260,160 | -51.6 | 3 | Universal |
| 6 | X-Men: The Last Stand | $7,820,253 | 2,812 | $2,781 | $216,218,853 | -51.4 | 4 | Fox |
| 7 | Garfield: A Tail of Two Kitties | $7,288,977 | 2,946 | $2,474 | $7,288,977 | -- | 1 | Fox |
| 8 | The Omen | $5,640,849 | 2,723 | $2,072 | $47,188,054 | -64.8 | 2 | Fox |
| 9 | The Da Vinci Code | $5,266,560 | 2,413 | $2,183 | $198,767,811 | -49.6 | 5 | Sony |
| 10 | Over the Hedge | $4,339,015 | 2,606 | $1,665 | $139,047,483 | -57.6 | 5 | Paramount |